Preschool wheezing and therapy
Can Montelukast play a role?
At the age of 6 50% of children had at least one wheezing episode, for which they underwent treatment with inhaled bronchodilators followed by corticostorides. In April, a group of Cambridge researchers reviewed the literature on leukotriene receptor antagonist (LTRA) as a replacement for inhaled corticosteroids: there isn’t scientific evidence to confirm the role of Montelukast. The National Institute for Health and Care guidelines on preschool wheezing propose the use of LTRA in addition to inhaled corticosteroids in the form of uncontrolled wheezing. Further studies are needed to clarify the answer.
“Is there a role for Montelukast in the management of viral-induced wheeze in preschool children?”, di Alisha Burman , Arch Dis Child. 2018 May;103(5):519-520.