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Asthma and COVID-19 risk
Considering the high incidence of asthmatic children and SARS-CoV-2 diffusion, there is a need for identify which children are at increased risk of serious COVID-19 outcomes. A Scottish study aimed to investigate risk factors for a severe outcome.
A Scottish study used data from dataset of Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 collected from March 2020 to July 2021 to identify which factors could increase risk of serious COVID-19 outcomes in asthmatic children aged 5-17 years. The study showed that in the group of asthmatic children (n = 4,339) hospital admission was higher than controls (n = 40,231) (1.5% vs 0.9%).The rate of COVID-19 hospital admission was higher also among children with markers of uncontrolled asthma defined by either previous asthma hospital admission (previous hospital admission vs no admission, HR 6.4 vs 1.36) or oral corticosteroid prescription in the previous 2 years (2/ ≥3 courses vs 0 course of corticosteroids, HR 3.53/3.38 vs 1.34). However, the number of COVID-19 related deaths was too small (n<5) to enable to carry out any statistical analysis. The Authors conclude that school-aged children with asthma, especially those poorly controlled, are at markedly increased risk of COVID-19 hospital admission and should be considered a priority for vaccinations.
Reference
Ting Shi.Risk of COVID-19 hospital admission among children aged 5-17 years with asthma in Scotland: a national incident cohort study. Lancet Respir Med 2022 Feb;10(2):191-198.
