Congenital central hypoventilation syndrome (CCHS), a rare disease caused by variants in the paired-like homeobox 2B (PHOX2B) gene, affects regulation of respiration necessitating lifelong assisted ventilation (AV). Most patients require full-time AV during infancy and some patients may sustain adequate spontaneous ventilation during wakefulness and change AV modalities at a later age.
News 2023 Selection: Sleep and Breathing Disorders
Congenital Central Hypoventilation Syndrome: Diagnosis and Long-Term Ventilatory Outcomes
Obstructive sleep apnea is associated with use of assisted ventilation among children with bronchopulmonary dysplasia hospitalized with respiratory illness: a nationwide inpatient cohort
Hypovitaminosis D and OSAS in children: is there any relationship?